RIKEN's New Research Center for Brain Science: RIKEN CBS Website

RIKEN BRAIN SCIENCE INSTITUTE (RIKEN BSI)

Events

[Journal Club]

“ Cognitive Brain Science Seminar ”

BSI Private Event

Add this Event to My Calendar

iCal Google
Other
Windows Live Calendar Yahoo! Calendar Microsoft Office Outlook Calendar
Email this event information

Print this Event

Date

February 24, 2011 10:15 - 11:00

Abstract

"How instructed knowledge modulates the neural systems of reward learning"

Recent research in neuroeconomics has demonstrated that the reinforcement learning model of reward learning captures the patterns of both behavioral performance and neural responses during a range of economic decision-making tasks. However, this powerful theoretical model has its limits. Trial-and-error is only one of the means by which individuals can learn the value associated with different decision options. Humans have also developed efficient, symbolic means of communication for learning without the necessity for committing multiple errors across trials. In the present study, we observed that instructed knowledge of cue-reward probabilities improves behavioral performance and diminishes reinforcement learning-related blood-oxygen level-dependent (BOLD) responses to feedback in the nucleus accumbens, ventromedial prefrontal cortex, and hippocampal complex. The decrease in BOLD responses in these brain regions to reward-feedback signals was functionally correlated with activation of the dorsolateral prefrontal cortex (DLPFC). These results suggest that when learning action values, participants use the DLPFC to dynamically adjust outcome responses in valuation regions depending on the usefulness of action-outcome information. Jian Li, Mauricio R. Delgado, and Elizabeth A. Phelps How instructed knowledge modulates the neural systems of reward learning PNAS 2011 108 (1) 55-60 http://www.pnas.org/content/108/1/55

More Detail

Language
English
Admission
BSI Private Event
RIKEN people can also attend this event.
Link
http://pdl.brain.riken.jp/staff/dalex/computational_neuroscience_seminar/
Host
David Alexander, Laboratory for Perceptual Dynamics